Procoagulant proteins derived from factor viii: c
CA 1341229 C · Owner: Genetics Institute, Llc · Inventors: Kaufman, Randal J.; Toole, John J. Jr.; Pittman, Debra D.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention relates to recombinant Factor VIII:c variants, methods to produce the variants and pharmaceutical compositions containing same. The variants of this invention are characterized by modification of one or more specific proteolytic cleavage sites encompassing the arginine residues at positions 220 226, 250, 279, 282, 336, 359, 562, 740 776, 1313, 1648, 1719 and 1721; and/or one or both of the lysine residues at positions 325 and 338 and/or serine-741. The variants possess similar or improved procoagulant activity and/or pharmacokinetic profiles compared to that of human Factor VIII:c.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted May 15, 2001. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended May 15, 2018.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.