Process for recovering microbially produced interferon-beta
CA 1340586 C · Owner: Thomson, Jody · Inventors: Thomson, Jody; Hershenson, Susan; Shaked, Ze'Ev
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
An approved procedure for the purification and renaturation of biologically active, bacterially produced IFN-beta is described. The partially purified material obtained by solubilization of isolated refractile bodies from the recombinant cells is treated to obtain reduction of the protein in the presence of a chaotropic environment and then oxidized after removal of the reducing agent. However, the chaotropic environment is retained during the oxidation. Upon removal of the chaotropic environment, a solubilizing additive is supplied to maintain the IFN-beta in solution. Further purification by conventional means may also be effected.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted June 8, 1999. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended June 8, 2016.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.