Thiazolyl derivatives useful as interediates for the preparation of cephem or cepham compounds

Abstract From the Canadian patent

Compounds of the formula:, (see fig. I) wherein R2 is a lower alkyl having 4 to 8 carbon atoms cycloalkyl, lower alkynyl having 2 to 6 carbon atoms halo(lower)alkyl, carboxy(lower)alkyl or esterified carboxy(lower)alkyl, R6 is amino or protected amino and R8, is hydrogen or lower alkyl, or the reactive derivatives at the carboxy group or salts thereof. These compounds are useful intermediates for the preparation of cephem or cepham compounds which can be employed for the treatment of infectious diseases caused by pathogenic microorganisms.