Process for the preparation of 2-arylpropionic acids

Abstract From the Canadian patent

A process for the preparation of a pharmaceutically active compound in a stereospecific form of the formula (see fig. I), or a pharmaceutically acceptable salt or ester thereof like an alkali metal salt or an alkaline earth metal salt or a pivaloyl ester, wherein R1 represents an optionally substituted aryl group such as a phenyl or naphthyl group optionally included in a heterocyclic ring system which is, optionally substituted, or represents a heteroaromatic ring system containing in addition to carbon atoms one or more atoms selected from nitrogen, sulphur and oxygen this ring, system being optionally substituted which comprises, subjecting a compound of the formula (see fig. II), …