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Expired Canadian patentCanada

Purification of stable water-soluble dioxetanes

CA 1340357 C · Owner: Applera Corporation · Inventors: Voyta, John C.; Edwards, Brooks

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Abstract From the Canadian patent

Methods are disclosed for purifying, chemiluminescent water-soluble 1,2-dioxetane derivatives suitable for use as reporter molecules in a variety of biological analytical systems including, enzyme-linked immunoassays, nucleic acid probe techniques, and structural determinations. The methods are based upon high pressure, medium pressure or low pressure liquid chromatography using as the stationary phase alkaline pH-stable compositions with the chromatographic characteristics of reversed-phase adsorbents, at alkaline pH values, and in the absence of acid-forming compounds or compounds with an unshared pair of electrons. Desalting of substantially pure water soluble 1,2-dioxetane derivatives …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Granted January 26, 1999. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended January 26, 2016.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledSeptember 14, 1989
GrantedJanuary 26, 1999
Term endedJanuary 26, 2016
Patent numberCA 1340357 C
Classification (IPC)C07D321/00 +2 more

Timeline

Timeline From CIPO dates

199019931996199920022005200820112014Application filedSep 14, 1989Patent grantedJan 26, 1999Term endedJan 26, 2016

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.