8-alkoxyquinolonecarboxylic acid salts thereof excellent in the selecti ve toxicity and process of preparing the same

Abstract From the Canadian patent

Quinolonecarboxylic acid derivatives of the following formula, (see fig. I), wherein R indicates a hydrogen atom or lower alkyl group R1, indicates a lower alkyl group, R2 indicates a hydrogen atom amino group or nitro group, X indicates a halogen atom and Z, indicates a halogen atom, piperazino group N-methylpiperazino, group, 3-methylpiperazino group 3-hydroxypyrrolidino group, or, pyrrolidino group of the following formula (see fig. II), (here, n is or 1, R3 indicates a hydrogen atom or lower alkyl group, R4 indicates a hydrogen atom, lower alkyl group or substituted lower alkyl group and R5 indicates a hydrogen atom lower, alkyl group, acyl group or alkoxycarbonyl group) the hydrates, …