Benzodiazepines, process and intermediates for the preparation thereof and their applications in therapy

Abstract From the Canadian patent

The invention relates to benzodiazepines of formula:, (see fig.I), in which R1 is H or halogen R2 is H or halogen, Ar is, indolyl, phenyl naphthyl, indolyl monosubstituted with a halogen or with a methoxy or phenyl monodi- or, trisubstituted with a halogen or with a methoxy or with a trifluoromethyl group, and n is 2 or 3; and their optical isomers. The compounds are useful chiefly for combating gastrointestinal disorders and disorders of the pancreas, the gallbladder and the appetite; pain.