Site-specific chiral ruthenium (ii) and cobalt (iii) anti-tumor agents
CA 1339360 C · Owner: Barton, Jacqueline K. · Inventors: Barton, Jacqueline K.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention concerns a coordination complex of the formula (R)2---M---(Y)2 wherein M comprises a suitable transition metal, e.g. cobalt or ruthenium R comprises, 1,10-phenanthroline or a substituted derivative thereof, Y comprises a labile ligand, e.g. chloride tartrate, malonate or ascorbate ion and R and Y are bonded to M by coordination bonds. A complex of this invention may be used for covalently labeling DNA with a complex of the formula (R)2---M wherein R and M are as previously defined. A complex of this invention which contains cobalt may also be used in a method for nicking DNA by effecting single-stranded scission of at least one phosphodiester bond of the DNA with ultraviolet …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted August 26, 1997. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended August 26, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.