High purity bone mineral

Abstract From the Canadian patent

The invention relates to an artificial bone mineral for use in medicine and to a process for preparing the same. The bone mineral has a crystal structure and mineral microstructure substantially the same as natural bone and thus permits physiologically controlled cell, mediated remodelling on implantation. The bone mineral however, has an organic impurity content below 150 parts per million. The bone mineral is produced by degrading and solubilizing degreased bone by heating with ammonia or a primary amine, and extracting the solubilized degradation products by washing with flowing water at temperatures below 60°C. If necessary the degrading and washing steps may be repeated to remove …