Vaccines obtained from antigenic gene products of recombinant genes

Abstract From the Canadian patent

A vaccine for the immunization of a vertebrate comprising a non-pathogenic microbe that expresses a recombinant gene derived from an organism that is a pathogen of or that produces an allergin of said animal where the gene codes for a gene product that is an antigen capable of being recognized by the immune system of the vertebrate and inducing antibody formation against the pathogen or allergen. Also disclosed is the use of microbes of the nature described above to produce nonliving vaccines comprising such gene products essentially in the absence of other antigenic material from the parent organism. There is also disclosed another vaccine of the same type which comprises an avirulent …