Enzyme-nucleic acid hydrazone and hydrazide conjugate compositions and methods
CA 1333366 C · Owner: Ghosh, Soumitra Shankar · Inventors: Ghosh, Soumitra Shankar
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A nucleic acid probe, wherein the label is a catalytically active enzyme, is provided. The nucleic acid of the probe is a DNA or a RNA and comprises a segment of at least 20 nucleotides in the sequence complementary to that of the target segment of the probe. In the probe, the nucleic acid and enzyme are covalently joined by a linker, which is bonded at one, end, to the 5'-carbon of the 5'-nucleotide of the nucleic acid and, at the other end, to the enzyme and which comprises an hydrazone or hydrazide group. Also provided is a nucleic acid, which is an intermediate for making a probe according to the invention and which is derivatized, at the 5'-carbon of the 5'-nucleotide with, a moiety …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted December 6, 1994. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended December 6, 2011.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.