Method, device and kit for measurement of tissue plasminogen activator activity

Abstract From the Canadian patent

A true activity of tissue plasminogen activator is determined by reacting a solid phase having bound thereto anti tissue plasminogen activator antibody IgG fragment having affinity to a site other than the active site of tissue plasminogen activator with tissue plasminogen activator in a sample and then measuring an activity of the reaction product preferably in terms of an amount of a substance released from a chromogenic peptide substrate. This measurement enables to use of whole blood or diluted blood as the sample and achieves high sensitivity and high accuracy in a short period of time.