Immunoenzymatic method for the determination of anti-plasmodium falciparum-sporozoite antibodies

Abstract From the Canadian patent

An immunoenzymatic method for the detection of anti-Plasmodium falciparum-sporozoite antibodies in a sample of human blood, which operates, in homogeneous phase and, under suitable conditions, with a synthetic polypeptidic antigen (P), a synthetic antigen-enzyme (P-E) conjugate wherein said antigen is capable of specifically reacting with the anti-Plasmodium falciparum-sporozoite antibodies (Ab) possibly present in the sample, and an inert substance capable of quantitatively precipitating the antibodysynthetic antigen-enzyme complex (Ab-P-E). The method thanks to its specificity, sensibility reproducibility and, rapidity, is particularly useful in the epidemiological investigations into …