Azetidinone intermediates for 1-carba(dethia)cephalosporins
CA 1330565 C · Owner: Eli Lilly And Company · Inventors: Vladuchick, William Charles; Morin, John Michael Jr.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Azetidinone-2 intermediates represented by the formula, wherein R is phenyl, phenoxy or thienyl R1 is, -CH=CH-COOR1' wherein R1' is an ester e.g. benzyl;, -CH2CH2COR2 where R2 is OH or imidazol-1-yl; -CH2CH2C(O)CH2COOR1' where R1' is an ester e.g. p-nitrobenzyl; and R', R'' and R''' are C1-C4 alkyl aryl or aralkyl; are converted to 1-carba(dethia)cephalosporin antibiotics. Preferably, R is phenoxy and the 1-silyl group is dimethyl-t-butylsilyl. Also provided is 3.beta.-phenoxyacetylamino-4.beta.-(2-carboxyethyl)azetidinone likewise useful in the preparation of 1-carbacephalosporin antibiotics.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted July 5, 1994. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended July 5, 2011.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.