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Expired Canadian patentCanada

Spontaneous vesiculation of multilamellar liposomes

CA 1330199 C · Owner: The Liposome Company, Inc. · Inventors: Madden, Thomas D.

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Abstract From the Canadian patent

A new method is disclosed for making unilamellar vesicles from multilamellar vesicles. Such vesicles are formed without the use of physical or chemical disruption processes known in the art for forming unilamellar vesicles. The liposomes are incubated at neutral pH at or near the transition temperature of the lipids used in low ionic strength media such, as distilled water. The liposomes may comprise bioactive agents and may be used in vivo or in vitro Lipid compositions are preferably a combination of the phospholipids dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylglycerol (DMPG) in about a 7:3 mole ratio.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Granted June 14, 1994. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended June 14, 2011.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledDecember 22, 1988
GrantedJune 14, 1994
Term endedJune 14, 2011
Patent numberCA 1330199 C
Classification (IPC)A61K9/13 +2 more

Timeline

Timeline From CIPO dates

19891992199519982001200420072010Application filedDec 22, 1988Patent grantedJune 14, 1994Term endedJune 14, 2011

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.