Process for recovering refractile bodies containing heterologous proteins from microbial hosts
CA 1329308 C · Owner: Cetus Corporation · Inventors: Dorin, Glenn; Hanisch, Wolfgang H.; Lin, Leo S.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A refractile material containing a heterologous protein is recovered from a host microorganism cell culture transformed to produce the protein. One recovery process involves disrupting the cell wall and membrane of the host cell removing greater than 99% by, weight of the salts from the disruptate redisrupting the desalted, disruptate, adding a material to the disruptate to create a density or viscosity gradient in the liquid within the disruptate and separating, the refractile material from the cellular debris by high-speed centrifugation. Another version of such a recovery process comprises the further steps of solubilizing the refractile material under reducing conditions, organically …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted May 3, 1994. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended May 3, 2011.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.