Process for the production of (+) biotin
CA 1322757 C · Owner: Lonza Ltd. · Inventors: Mcgarrity, John; Tenud, Leander
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
PROCESS FOR THE PRODUCTION OF (+) BIOTIN ABSTRACT OF THE DISCLOSURE, Process for the production of (+) biotin. The process comprises catalytically hydrogenating a compound of the formula:, I, with hydrogen, separating the desired diastereomer of the formula:, II, introducing a protective group converting the, diastereomer by further reaction with a thiocarboxylic acid salt derivative into the corresponding thiolactone by a Grignard reaction and subsequently splitting off of water or a compound of the formula:, (C6H5)3p?(CH2)4COOR3.X? III 58, in the presence of a base to a compound of the formula: IV, catalytically hydrogenating the compound and then cleaving the protective groups to form …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted October 5, 1993. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended October 5, 2010.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.