Substituted imidazolyl-alkyl-piperazine and-diazepine derivatives

Abstract From the Canadian patent

Substituted imidazolyl-alkyl-piperazine and diazepine derivatives of Formula A:, FORMULA A wherein:, R1 is aryl;, R2 is aryl, lower alkyl or hydrogen;, R3 is lower alkyl, hydroxy or hydrogen;, R4 is aryl;, R5 is aryl; m is two or three;, n is zero, one or two provided that when R3 is hydroxy, n is one or two; and, q is zero, one, two, or three; and the pharmaceutically acceptable salts thereof are, useful for treating mammals having a variety of disease states, such as stroke, epilepsy or epileptic psychotic symptoms, hypertension, angina, migraine arrhythmia, thrombosis, embolism, acute cardiac failure irritable, bowel syndrome, neurodegenerative diseases such as Alzheimer's or …