Method for stabilizing heterologous protein expression and vectors for use therein
CA 1320162 C · Owner: California Biotechnology Inc. · Inventors: Hilliker, Sandra; White, R. Tyler
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Abstract of the Invention, The present invention provides a method for stabilizing heterologous protein expression in bacteria by using a 3' truncated chloramphenicol acetyltransferase (CAT) gene fused in frame with a gene encoding a heterologous protein. When expressed in a bacterial host the, resulting hybrid gene produces a fusion protein in recoverable yield. Cleavage sites separating the CAT and heterologous protein are also provided to facilitate isolation and purification of the desired heterologous protein The invention further provides bacterial vectors containing the hybrid gene fusions for expression of the fusion protein comprising the desired heterologous protein.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted July 13, 1993. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended July 13, 2010.
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Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.