Tetralin derivatives, their preparation and their use

Abstract From the Canadian patent

Disclosed are novel tetralin derivative of the formula (I):, (I), where R1 is hydrogen C1-C4-alkyl, C1-C4-alkoxy or halogen, R2 is hydrogen C1-C6-alkyl or C3-C6-cycloalkyl, X, is -CH2-CO- -CH2-CHOH, -CH2-C(R4)OH-, -CH2-C(OCOR4)H- -CH2-C(R4)(OCHOR5)-, -CHOH-CHOH-, -CH=CH- -CH(OCOR4), -CH(OCOR4)-, -CH2-CH(OR4)- (where R4 and R5 are each C1-C4alkyl) and R3 is nitrile, C2-C10-ketal or -CH(R7)(R8)- or -CO-R9, where R7 is hydrogen or C1-C3-alkyl R8 is hydrogen, C1-C3-alkyl or -OR10 or -NR11R12 (where R10 R11 and R12 are, each hydrogen, C1-C4-alkyl C2-C20-alkanoyl or unsubstituted, or substituted benzoyl) and R9 is hydrogen halogen, C1-C4-, alkyl, azido, or -OR13 (where R13 is hydrogen or …