Process for the preparation of methylene derivatives of androsta-1,4-diene-3,17-dione
CA 1316914 C · Owner: Lombardi, Paolo · Inventors: Lombardi, Paolo; Longo, Antonio
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to a new process for the preparation of known aromatase inhibitors of the following formula wherein, each of R1 and R3, independently is hydrogen or C1-C6 alkyl;, R2 is hydrogen halogen or C1-C6 alkyl and, R4 is hydrogen or fluorine; the process comprising subjecting to Mannich reaction a compound of formula wherein, R1,R2,R3 and R4 are as defined above and then oxidizing the, respective 6-methylene derivative thus obtained by methods known per se.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted April 27, 1993. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended April 27, 2010.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.