Immunologically active synthetic peptides useful for preparing an antimalarial vaccine

Abstract From the Canadian patent

Synthetic peptides consisting of at least two consecutive repeating units of the sequence (Ala-Asn-Asn-Pro) are powerful immunogens in experimental animals. The antibodies which form recognise both the synthetic peptides and the immunodominant epitope of the circumsporozoitic peptide of Plasmodium falciparum. These peptides, obtainable in pure form, are particularly useful for preparing antimalarial vaccines and diagnostic kits for the determination of malarial affections.