Tetrahydronaphthaline and indane derivatives

Abstract From the Canadian patent

Abstract, The compounds of the general formula I, wherein X and Y represent -CH2- or >C(CH3)2; Z represents a residue -CHR8-, >CO, >CR8OR7 -CHR8-CHR8-, -CHOR7-CH2-, -CO-CHOR7- or -CHOR7-CHOR7-; R1 represents a 5- or 6-membered monocyclic heterocyclic residue which can be C-substituted by halogen, lower-alkyl, lower-alkoxy acyloxy, nitro, hydroxy, amino, lower-alkylamino or di-lower-alkylamino and/or which can be substituted on a ring -NH- group by lower-alkyl: R2 and R3 represent hydrogen, lower-alkyl, trifluoromethyl or halogen and one of the residues R2 and R3 represents trifluoromethyl or lower-alkyl: R4 and R5 represent hydrogen, alkyl, alkoxy or halogen: R6 represents hydrogen, …