Technetium chelates to be used for determining the renal function

Abstract From the Canadian patent

CIL 0132, ABSTRACT:, The invention relates to a technetium chelate of the general formula, (I), wherein, X is a sulphur atom or an imino group Z is a hydrogen atom, a carboxy group, an alkoxycarbonyl group having 1-4 carbon atoms, an aminocarbonyl group, a sulpho group, an aminosulphonyl group or a carboxymethylaminocarbonyl group, Tc represents technetium-99m R1 is a hydrogen atom or an alkyl group having 1 or 2 carbon atoms, and, R2, R3, R4 and R5 are equal or different and represent hydrogen atoms or branched or non-branched alkyl groups having 1-4 carbon atoms, which alkyl groups are optionally substituted with an amino group, a hydroxy group, a mercapto group a halogen, atom, a carboxy …