Process for preparing alpha-(alkylphenyl) -4-(hydroxydiphenylmethyl)-1-piperidine butanol
CA 1314893 C · Owner: Erregierre Industria Chimica S.P.A. · Inventors: Molinari, Egidio
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for preparing alpha-(alkylphenyl)-4-(hydroxy diphenylmethyl)-1-piperidine butanol of formula (I), in which R is a C1-C6 alkyl, consisting of reacting an isonipecotate of formula (II):, (II), in which R' is a C1-C5 alkyl or an arylalkyl such as benzyl with, 1-(alkylphenyl)-4-chlorobutanol (III) or with 1-(alkylphenyl)-3chloropropylketone (VI), in both of which the alkyl group is C1- C5, to obtain the compound (IV) either directly or after reduction of the ketone group:, (IV), and reacting (IV) with phenylmagnesium halide (V) to obtain (I).
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted March 23, 1993. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended March 23, 2010.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.