Heterologous system for the detection of chemically-labeled dna and other biological materials providing a receptor or target moiety thereon

Abstract From the Canadian patent

The detection and/or identification of materials of interest, such as biological materials e.g. chemically, labeled DNA, which provide a receptor thereon is, improved by employing a heterologous detection system by employing more than one binding reactions such as, reactions involving the affinity of lectin to a glycoprotein or sugar group and the affinity between biotin and avidin or streptavidin, avidin itself being a glycoprotein. Particularly useful in the heterologous detection system are biotinylated lectins such as, biotinylated Concanavalin A, biotinylated dextran lectin-, glycoprotein complexes, such as lectin-avidin and lectinenzyme complexes and streptavidin-biotinylated enzyme …