Transdermal estrogen/progestin dosage unit, system and process

Abstract From the Canadian patent

Transdermal estrogen/progestin absorption dosage units have been developed which comprise a backing layer an, adjoining polymer layer is an adhesive layer in which at least minimum effective dose of an estrogen is dissolved or microdispersed. Adhered to the polymer layer is an adhesive layer in which is dissolved and/or microdispersed at least minimum doses of progestin. Presently preferred is use of the natural estrogen, 17-beta-estradiol or ethinyl estra-, diol or combinations thereof and of the progestin norethin-, drone or norgestimate or combinations thereof. The units have biologically acceptable adhesive and polymer layers. The adhesive layer can have dispersed one or more skin …