Preparation of retrovirus-free immunoglobulins
CA 1312546 C · Owner: Mitra, Gautam · Inventors: Mozen, Milton M.; Mitra, Gautam
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Invention: PREPARATION OF RETROVIRUS-FREE IMMUNOGLOBULINS Inventors: GAUTAM MITRA and MILTON M. MOZEN Abstract of The Disclosure, The effects of Cohn-Oncley cold alcohol fractionation on infectivity of two prototype retroviruses mouse xenotropic, type C and the LAV strain of AIDS retrovirus result in a significant reduction in retrovirus titer. At least a 100,000-fold reduction of LAV was obtained when fractionating plasma to fraction II. Adjustment to pH 4.0 at filtrate III was as effective for viral inactivation as was precipitation of fraction II from filtrate III with 25% ethanol. Liquid immunoglobulin preparations spiked with LAV and incubated at 27° C for 3 days resulted in an …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted January 12, 1993. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended January 12, 2010.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.