Desazapurine-nucleoside derivatives, processes for the preparation thereof, pharmaceutical compositions containing them and the use thereof fornucleic acid sequencing and as antiviral agents

Abstract From the Canadian patent

Desazapurine-nucleoside derivatives processes for the, preparation thereof pharmaceutical compositions, containing them and the use thereof for nucleic acid sequencing and as antiviral agents, The present invention provides desazapurinenucleoside derivatives of the general formula:- (I), wherein X is a nitrogen atom or a methine radical W is, a nitrogen atom or a , radical, R1 R2, R3 and R4, which can be the same or different 3 are hydrogen or halogen atoms, hydroxyl or mercapto groups lower alkyl, lower alkylthio, lower alkoxy aralkyl, aralkoxy or, aryloxy radicals or amino groups optionally substituted once or twice, R5 is a hydrogen atom or a hydroxyl group R6 and R7 are each hydrogen …