Process for the preparation of 4-acylamino-2-aminoalkoxy-benzenes

Abstract From the Canadian patent

Abstract, A process for the preparation of 4-acylamino-2-aminoalkoxybenzenes of the general formula (1) (1), in which R denotes an alkyl-C1-C6- or alkoxy-C1-C4alkylene-C1-C4 group and R' denotes a methyl or ethyl group, by pumping a solution or suspension of a 2,4-dinitroalkoxybenzene of the general formula (2) (2), in which R has the abovementioned meaning in a butyl ace-, tate into a stirred suspension of a nickel catalyst on a kieselguhr carrier in butyl acetate, which has been initially introduced into an autoclave, at a hydrogen pressure of about 5 to about 50 bar, and a temperature of about 60 to about 120°C, at a rate which corresponds to the rate of hydrogenation of …