Method for the preparation of a coated solid medicament

Abstract From the Canadian patent

Instead of using a uniform aqueous solution of a water-soluble cellulose ether as a coating liquid of solid medicament forms e.g. granules and tablets, to form a film-forming layer an aqueous, dispersion of a cellulose ether which is soluble in cold water but, insoluble in hot water is used as a coating liquid at a temperature higher that the solubilization temperature i.e. the critical point of, the solubility behavior followed by plasticization of the cellulose ether particles with water to cause fusion thereof. The coating liquid is freed from the limitation by the flowability even when the content of the cellulose ether is much higher than in the conventional solution-type coating …