2h-1-benzapyran compounds

Abstract From the Canadian patent

Compounds of formula (I) and pharmaceutically acceptable salts thereof:, (I), wherein: Y is N or (when R3 is hydroxy, C1-6 alkoxy or C1-7 acyloxy) CH;, one of R1 and R2 is hydrogen or C1-4 alkyl and the other is C1-4 alkyl or R1 and R2 together are C2-5polymethylene;, R3 is hydrogen, hydroxy C1-6 alkoxy or, C1-7 acyloxy;, R4 is a C3-8 cycloalkyl group or a C1-6 alkyl group optionally substituted by a group R7 which is hydroxy C1-6 alkoxy, amino optionally substituted by one or two C1-6 alkyl groups; C1-7 alkanoylamino, C3-8 cycloalkyloxy, C3-8 cycloalkylamino, or 1,3-dioxo-2isoindoline;, when Y is N, R5 is hydrogen C1-6 alkyl optionally, substituted by halogen hydroxy, C1-6 alkoxy, C1-6, …