Composition for transdermal therapeutic systems of loop diuretics and a process for its preparation

Abstract From the Canadian patent

A description is given of a composition for transdermal therapeutic systems, which contains as active compound furosemide, piretanide or lemidosul, or a physiologically tolerated salt of these loop diuretics in a base composed, of a fatty acid alkanolamide or of a fatty acid alkanol-, amide mixture having 8-18 carbon atoms in the fatty acid residue and 2 to 6 carbon atoms and 1 to 3 hydroxyl groups in the alkanolamide residue, and, where appropriate of, a carboxylic ester, or of a carboxylic ester mixture in, each case having 1-22 carbon atoms in the carboxylic acid moiety and 1-22 carbon atoms in the alcohol moiety.