Enhanced expression and stabilization of gene products in microorganisms using short selected leader signal sequences
CA 1306208 C · Owner: National Research Council Of Canada · Inventors: Narang, Saran A.; Wu, Ray J.; Sung, Wing L.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Saran A. Narang, Winq L. Sung ABSTRACT, This invention concerns the employment of DNA sequences comprising (a) a sequence coding for a desired polypeptide, and; (b) a selected leader signal sequence coding for a range of from a tri-peptide to about one third of the size of peptide coded by sequence (a) said, selected leader signal sequence being chosen to enhance the effective expression of, and/or stabilize the polypeptide coded by sequences (a) and (b) when said DNA sequence resides and is expressed in a foreign host microorganism. The polypeptide products of sequences (a) and (b) preferably should be readily cleavable from each other to allow for simple purification of such products.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted August 11, 1992. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended August 11, 2009.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.