Ovine inhibin
CA 1305829 C · Owner: Vale, Wylie Walker, Jr. · Inventors: Bardin, C. Wayne; Spiess, Joachim; Rivier, Jean Edouard Frederic
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A 34,500-dalton protein with inhibin activity is isolated from ram rete testis fluid using reverse-phase high-performance liquid chromatography and gel filtration. The isolated molecule is composed of two chains having molecular weights of about 18,000 and about 16,500 Daltons, which are bound together by disulfide bonding and the longer of which is likely glycosylated. Microsequencing revealed the NH2-terminal portion of the 18kD chain to be . This 34.5kD, protein specifically inhibits basal secretion of FSH but not of LH, in a rat anterior pituitary monolayer culture system, exhibiting a half-maximal effective dose of 0.3 ng/ml. Furthermore, antibodies raised against a synthetic replicate …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted July 28, 1992. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended July 28, 2009.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.