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Expired Canadian patentCanada

Production of interferon gamma

CA 1304704 C · Owner: Yeda Research And Development Co. Ltd. · Inventors: Rubinstein, Menachem; Revel, Michel; Mory, Yves

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Abstract From the Canadian patent

Interferon .gamma. is produced in higly purified form (activity exceeding 108 units/ml-day) by CHO cells cotransformed by a first plasmid bearing the genomic human interferon gene under the control of the SV40 early promoter, and a second plasmid bearing a DHFR gene under similar control. Methotrexate selection yielded a clone which was a particularly efficient producer. Production of interferon .gamma. may also be facilitated by a Harvey sarcoma virus enhancer sequence.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Granted July 7, 1992. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended July 7, 2009.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledApril 26, 1985
GrantedJuly 7, 1992
Term endedJuly 7, 2009
Patent numberCA 1304704 C
Classification (IPC)C12N15/23 +2 more

Timeline

Timeline From CIPO dates

19861989199219951998200120042007Application filedApril 26, 1985Patent grantedJuly 7, 1992Term endedJuly 7, 2009

Sources & verification

Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.