Immunoconjugates and methods for their use in tumor therapy
CA 1304293 C · Owner: Hellstrom, Karl E. · Inventors: Hellstrom, Karl E.; Lavie, Efraim; Hellstrom, Ingegerd E.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Novel pH-sensitive immunoconjugates which dissociate in low-pH tumor tissue, comprising a chemotherapeutic agent and an antibody reactive with a tumor-associated antigen are described. The chemotherapeutic agent is coupled to the antibody by a link which is unstable in low pH. The link may comprise a spacer consisting of a polyamino acid Rep-, resentative antibodies for use in these immunoconjugates include monoclonal antibodies which are not internalized by tumor cells. 149Z0531D7.9
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted June 30, 1992. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended June 30, 2009.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.