1,3-dihydro-6-¬1-cyano-1-isopropyl-n-phenethyl-n-methyl- aminoalkyl -7-hydroxy-furo-(3,4-c)-pyridine derivatives

Abstract From the Canadian patent

This invention relates to new 1,3-dihydro-6- l-cyano-lisopropyl-N-phenethyl-N-methyl- .omega. -aminoalkyl -7-hydroxy-furo- (3,4-c)-pyridine deriva- tives of the general formula wherein, each of A1 and A2 independently represents various substituents and to pharmaceutically acceptable salts of said derivatives, to a process for the preparation of the same comprising reacting, in stoichiometric proportions at, 15-65°C, in dimethylsulphoxide, a 6-(l-cyano-2-methyl-propyl)- 7-hydroxy-furo-(3,4-c)-pyridine derivative with the appropriate N-methyl-N-phenethyl- .omega. -aminoalkyl choride and finally, to a therapeutic composition of matter comprising as an essential ingredient therein an effective …