12b-substituted 1-hydroxymethyl-octahydroindolo¬2,3-a - quinolizine derivatives, process for the preparation and pharmaceutical compositions containing them

Abstract From the Canadian patent

12b-Substituted 1-hydroxymethyl-octahydroindolo2,3-aquinolizine derivatives, process for the preparation and pharmaceutical compositions containing them A b s t r a c t, The invention relates to new racemic and optically active 12b-substituted 1-hydroxymethyl-octahydroindolo- 2,3-aquinolizine derivatives of the formula (I) (I), wherein, R1 and R2 are the same or different and represent hydrogen halogen, nitro, amino, hydroxyl, alkyl having from 1 to 6 carbon atoms or alkoxy having from 1 to 6 carbon atoms;, R3 and R5 are the same or different and represent hydrogen alkyl having from 1 to 6 carbon atoms or aralkyl having from 1 to 6 carbon atoms in the alkyl moiety; R4 is alkyl having from 1 …