Piperazine derivatives and process for the preparation thereof
CA 1300141 C · Owner: Tajthy, Eva J. Nee Juhasz · Inventors: Reiter, Klara Nee Esses; Budai, Zoltan; Mezei, Tibor
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A b s t r a c t, the invention relates to a new and improved process for the preparation of 8-{4- 4-(2-pyrimidinyl)- -l-piperazinyl-butyl}-8-aza-spiro 4.5decane-7,9- -dione of the Formula I, (I), and pharmaceutically acceptable acid addition salts thereof, which comprises hydrogenating a compound of the general Formula II, (II), (wherein A stands for -C?C- or -CH=CH-) and if desired, converting the compound of the Formula I thus obtained into a pharmaceutically acceptable acid addition salt thereof. The compound of the Formula I is a known anxioselective agent. The invention also relates to intermediates used in the above process and a method for the preparation thereof.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted May 5, 1992. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended May 5, 2009.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.