3-phenyl-1-propanones, process of preparing thereof and method of treating arrhythmias

Abstract From the Canadian patent

Therapeutically useful 1-3-(2-dialkylaminoethoxy)- 2-thienyl-3-phenyl-1-propanones of the formula (I), and acid addition salts thereof, wherein R and R1 each are hydrogen or methyl, R2 and R3 which are the same or different, each are alkyl cycloalkyl, alkenyl or alkynyl each containing up to 8 carbon atoms, or, R2 and R3 together with the nitrogen atom to which they are attached form a 5 to 7-membered saturated ring or a saturated heterocyclic ring which may contain optionally an oxygen or nitrogen atom as further hetero atom in the ring a further nitrogen atom being unsubstituted or substituted by an alkyl radical containing 1 to 3 carbon atoms. The compounds are useful for the treatment …