Process for the preparation of new 2-(2-thienyl)- imidazo(4,5-c)pyridine derivatives and pharmaceutically usable acid addition salts thereof

Abstract From the Canadian patent

The invention relates to a process for the preparation of new 2-(2-thienyl)imidazo(4,5-c)pyridine derivatives of the general formula, wherein R1 denotes lower alkyl R2 denotes hydrogen or, methyl and n denotes 0 or 1 and pharmaceutically usable, acid addition salts thereof by reacting a thiophenecar-, boxylic acid chloride of the general formula III with a diaminopyridine of the general formula IV of the description to give an isomer mixture consisting of amides of the general formula, V, wherein R1 and R2 are as defined in formula I one of, the symbols A and B denotes the =N atom and the other in each case denotes =CH-, then cyclizing the isomer mixture in the form of the hydrochlorides …