4-substituted 10-cyanomethylenepyrrolo 4,3-e-benzazepines

Abstract From the Canadian patent

Disclosed are new 4-substituted 10-cyanomethylenepyrrolo4,3-e-benzazepines of the formula (I): (I), where R1 is hydrogen or halogen, alkyl trifluoromethyl or alkoxy, R2 and R3 are hydrogens or halogens R4 is hydrogen, alkyl or aralkyl where the aromatic system may be substituted by halogen, alkyl or methoxy radical and A is an amino, -NR5R6 where R5 and R6 form, together with the nitrogen atom connecting them, a 5 to 7-membered saturated ring which may contain a nitrogen or oxygen as further hetero atom, it being possible for an additional nitrogen to be substituted by alkyl, hydroxyalkyl, alkoxyalkyl cycloalkyl or cycloalkylmethyl, alkynyl and additionally by oxygen in the form of a …