Method for enhancing the safety of metal-ligand chelates as magnetic resonanis imaging agents and x-ray contrast agents
CA 1295237 C · Owner: Mallinckrodt, Inc. · Inventors: Vanderipe, Donald R.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Abstract of the Disclosure, Paramagnetic chelates as for example, Gadolinium, diethylenetriaminepentaacetic acid (DTPA) manganese, ethylenediaminetetraacetic acid (EDTA) and others used as, magnetic resonance imaging contrast agents are more toxic acutely when injected in high concentration or at rapid rates. The use of effective amounts of calcium in the form of, calcium chloride, calcium gluconate or balanced salt, solutions substantially reduces this toxicity without the need to add additional ligand.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted February 4, 1992. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended February 4, 2009.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.