Optically active (meth)acrylamides, polymers thereof, process for their preparation, and their use for racemate resolution

Abstract From the Canadian patent

In the chromatographic separation of a mixture of antipodes of optically active chemicals by passing a solution of such mixture over an optically active adsorbent to effect adsorption, and then eluting the adsorbed material, the improvement which comprises employing as the adsorbent particles of an optically active and cross-linked polymer containing the repeating structural unit, in which, R1 represents hydrogen or methyl and, R2 represents one of the stereoisomers of the eight possible stereoisomeric forms of each of the optically active radicals of the formulae or, Improved separation results. The pure monomers are also new.