Production of 2-bromo-alpha-ergocryptine and its acid addition salts
CA 1294956 C · Owner: Opalka, Miroslav · Inventors: Krajicek, Alois; Stuchlik, Josef; Sedmera, Petr
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
2-Bromo-alpha-ergocryptine the potent inhibitor, of prolactin /luteotropic hormone/ is prepared in high, yield and purity grade by the bromination of alpha-ergocryptine with elemental bromine in chlorinated aliphatic hydrocarbons and/or tetrahydrofuran in the presence of catalytic amounts of Lewis acids, preferably boron trifluoride, in the temperature range of from -40 to 0°C and optionally converted as known per se into its acid addition salt, preferably methanesulfonate.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted January 28, 1992. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended January 28, 2009.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.