Preparation of substituted 8-thiotetrahydroquinoline derivatives

Abstract From the Canadian patent

The invention relates to compounds of formula I ( I ), wherein X represents an oxygen or sulphur atom or a group of formula -NH-, -NAlk- (in which the substituent Alk represents a C1-6 alkyl group) or -NH-?-; and R1 and R2 which may be the same or different, each represents a hydrogen atom or a phenyl or naphthyl group or, together with the carbon atoms to which they are attached, represent a phenyl group which, phenyl group may optionally be substituted by a C1-6 alkyl C1-6, alkoxy or C1-6 alkylthio group, by one or more halogen atoms by, a nitro group, by a trifluoromethyl group or by a group, of formula -CH2-?O-Alk (in which the substituent Alk represents a C1-6 alkyl group), and to …