Cycloalkyl-substituted 4-aminophenyl halo derivatives and process for their preparation
CA 1292239 C · Owner: Lombardi, Paolo · Inventors: Crugnola, Angelo; Di Salle, Enrico; Lombardi, Paolo
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to cycloalkyl-substituted 4-aminophenyl halo derivatives of formula (I) (I), wherein, n is an integer of 1 to 5; A is> C=O or -CH2- and B is, independently -O-, -NH- or, -CH2-; and, either R is halogen and R1 is unsubstituted C1-C4 alkyl; or R is hydrogen and R1 is C1-C4 alkyl substituted by 1 to 4 halogen atoms, including the pharmaceutically acceptable salts thereof. The compounds of the invention show aromatase inhibiting activity and can find use, for example, in the treatment of estrogen-dependent tumors and of prostatic hyperplasia.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted November 19, 1991. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended November 19, 2008.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.