Antidepressant 2-(4,5-dihydro-1h-imidazolyl)-dihydro-1h- indoles, -tetrahydroquinolines and -1h-indoles
CA 1291759 C · Owner: Hlasta, Dennis J. · Inventors: Hlasta, Dennis J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
2-(4,5-Dihydro-1H-imidazol-2-yl)-2,3-dihydro-1Hindoles, 2-(4,5-dihydro-1H-imidazol-2-yl)-1,2,3,4-tetrahydroquinolines and 2-(4,5-dihydro-1H-imidazol-2-yl)-1Hindoles of the formulae below, useful as antidepressant agents are prepared by reacting a respective lower-alkyl 2,3-dihydro- 1H-indole-2-carboxylate, 1,2,3,g-tetrahydroquinoline-2carboxylate or 1H-indole-2-carboxylate derivative with ethylenediamine or an N-lower-alkylethylenediamine in the presence of a Lewis-type acid:, (I), (II) (III), (where, in the compounds of formula I: R' is hydrogen, halogen or benzyl;, R" is hydrogen or lower-alkyl; R1 is hydrogen, lower-alkyl, lower-alkenyl lower-alkoxy-, lower-alkyl, phenyl or …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted November 5, 1991. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended November 5, 2008.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.