Reconstituted basement membrane complex with biological activity
CA 1291432 C · Owner: Martin, George Reilly · Inventors: Kleinman, Hynda Karen; Martin, George Reilly
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention discloses a biologically active basement membrane composition. When polymerized under physiological conditions, the composition forms gel-like structures whose ultrastructure resembles interconnected thin sheets of the lamina densa zone of basement membrane. The major components of the composition include laminin, type IV collagen heparan, sulfate proteoglycan, entactin and nidogen. These components polymerize in constant proportions when redissolved and allowed to reconstitute. Molecular sieve studies on the soluble extract demonstate that laminin, entactin and nidogen are associated in a large but dissociable complex. The reconstituted matrix is biologically active …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted October 29, 1991. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended October 29, 2008.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.